Anime and Ponies are two of the most awesome things in this world right now, and only one thing could be better. Anime ponies. The closest thing to an anime pony I've ever seen is Ponyta/Rapidsh in the Pokemon Kanto episodes.
One of the main reasons why I love anime so much is because of the action and (obviously) the legit animation. Let's just take a minute and think about how awesome it would be if someone made a MLP anime crossover fan video and put it on YouTube. I will wait for the day, becuase I am much too lazy to make something like that, haha.